5-MeO-DMT is a natural psychedelic drug found in the venom of the Colorado River toad, Bufo Alvarius, also known as the Sonoran Desert toad. When smoked, it induces a short but intense psychedelic experience, with hallucinogenic effects significantly stronger than those induced by DMT, the primary psychoactive molecule found in Ayahuasca.

 

Despite this, the difference between 5-MeO-DMT and DMT is just a single Methoxy group, and it is structurally similar to other psychedelic drugs such as psilocybin and DMT. This psychedelic drug is also present in at least nine families of plants, trees, and shrubs and has been used for at least 3000 years in the form of crushed seeds known as ‘Yopo’, which are still used in spiritual ceremonies in Venezuela, Columbia, and Brazil.

 

The ‘trip’ usually lasts less than 30 minutes when smoked. Bufo is considered a key that leads one to their inner self; it can be likened to other practices such as Kundalini, Holotropic Breathwork, and meditation.

 

Participating in a Bufo Ceremony is a unique experience for each person. It is considered an opportunity to tap into oneness, heal ancestral trauma, awaken in a world of slumber, break free from the matrix, forgive, accept, and remember one's true self. It is believed to reveal the inherent beauty within and release individuals from years of grief, leading them to recognize the joy of their true nature. The experience is said to show the symphony of presence, absolute stillness, and the coexistence of everything and nothing at the same time.

 

The Bufo experience is described as a dissolving into an omniscient state of Oneness where there is no difference between "God" and the individual. It is believed to be a conscious love that is more intelligent than anything previously known, a love that transcends the need for physical form while paradoxically manifesting itself in all of creation. The encounter is said to provide a cosmic vibratory re-attunement.